Study Finds the Role of Endemic Coronaviruses-Induced Cross-Immunity in Protection against Severe COVID-19 Researchers examined whether earlier exposure to Coronaviruses (CoVs) causes Cross-reactive immunity that shields adults against severe coronavirus illness in a recent study published in PNAS (COVID-19).
Epidemiological studies have repeatedly demonstrated that past exposure to SARS- infection and severe COVID-19 imparts some resistance to SARS-Coronaviruses-2 infection and non-severe acute respiratory syndrome Coronaviruses 2 (SARS-) infection.
The development of Cross-reactive immunity in early children is most likely to blame, although it is yet unclear how this possible Cross-protection confers immunity against SARS-infection in adults. Furthermore, it is still unclear how well the Cross-reactive antibodies evoked fight the SARS-infection.
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